VI har åbent på NØRREBRO! Du kan stadigvæk få din yndlings bowl. Hvis du bor lidt for langt fra Nørrebro, til at kunne bevæge dig selv hen til butikken, så husk at vi leverer til døren!


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Non-celiac gluten sensitivity (NCGS) or gluten sensitivity[14] is defined as "a clinical entity induced by the ingestion of gluten leading to intestinal and/or extraintestinal symptoms that improve once the gluten-containing foodstuff is removed from the diet, and celiac disease and wheat allergy have been excluded".[15]

NCGS is included in the spectrum of gluten-related disorders.[3][4] The definition and diagnostic criteria of non-celiac gluten sensitivity were debated and established by three consensus conferences.[4][14][15][16][17]

The pathogenesis of NCGS is not yet well understood, but the activation of the innate immune system, the direct cytotoxic effects of gluten and probably other wheat components, are implicated.[3][18][19] There is evidence that not only gliadin (the main cytotoxic antigen of gluten), but also other proteins named ATIs which are present in gluten-containing cereals (wheatryebarley, and their derivatives) may have a role in the development of symptoms. ATIs are potent activators of the innate immune system.[3][20] FODMAPs, especially fructans, are present in small amounts in gluten-containing grains and have been identified as a possible cause of some gastrointestinal symptoms in NCGS patients.[3][10][21][20] As of 2019, reviews have concluded that although FODMAPs may play a role in NCGS, they only explain certain gastrointestinal symptoms, such as bloating, but not the extra-digestive symptoms that people with NCGS may develop, such as neurological disordersfibromyalgia, psychological disturbances, and dermatitis.[20][9][3]

For these reasons, NCGS is a controversial clinical condition[22] and some authors still question it.[23][24] It has been suggested that "non-celiac wheat sensitivity" is a more appropriate term, without forgetting that other gluten-containing cereals are implicated in the development of symptoms.[11][23]

NCGS is the most common syndrome of gluten-related disorders[4][25] with prevalence rates between 0.5–13% in the general population.[13] As no biomarker for diagnosing this condition is available, its diagnosis is made by exclusion of other gluten-related disorders, namely by excluding celiac disease and wheat allergy.[22] Many people have not been diagnosed following strict criteria and there is a "fad component" to the recent rise in popularity of the gluten-free diet, which leads to debate surrounding the evidence for this condition, its relationship to celiac disease and to irritable bowel syndrome.[3][5] People with non-celiac gluten sensitivity may remain in a "no man's land", without being recognized by the specialists and lacking the adequate medical care and treatment.[26] Most of these people have a long history of health complaints and unsuccessful consultations with numerous physicians, and this is the reason why many of them end up resorting to a gluten-free diet and a self-diagnosis of gluten sensitivity.[27]

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